2016 Volume 7 Issue 2 Pages 113-117
Except for pediatric and neonatal cases, there are currently no specific criteria regarding the selection of hemofilters for continuous renal replacement therapy (CRRT). In the present study, we retrospectively assessed the influence of the membrane area on the lifetime of polysulfone (PS) and cellulose triacetate (CTA) hemofilters. We examined 36 patients who underwent 70 CRRT sessions at the Saitama Medical University International Medical Center. The sessions were divided into 2 groups based on the membrane area of the filter used：L group （membrane area＞1.0m2） or S group (membrane area＜1.0m2). The rate of achievement of hemofilter lifetime of 24 hours and the reasons for circuit exchange, with the use of PS and CTA hemofilters, were compared. With regard to the rate of achievement of hemofilter lifetime of 24 hours, no difference was observed between the L and S groups when PS hemofilters were used. In contrast, this rate was significantly higher in the L group than in the S group (p＜0.05) when CTA hemofilters were used. With regard to reasons for circuit exchange, abnormalities in filtration pressure were not observed in the L group when CTA hemofilters were used. In conclusion, membrane area could affect the lifetime of CTA hemofilter through the difference in filtration performance.
