2016 Volume 7 Issue 2 Pages 152-156
Recent advances in reverse osmosis system (RO system) based on stricter administration standards for water quality increased the availability of ultra-pure dialysis fluid. Thereby, on-line HDF (OHDF) has become common among dialysis facilities in Japan. We successfully introduced the RO system for multipatient in the ICU from January 2012, and safely carried out acute blood purification therapy including continuous OHDF (OL-CHDF) using the RO system. We performed the continuous blood purification therapy in 16 cases for two years. The survival rate from ICU was 88%. We initially experienced issues to preserve the quality of ultra-pure dialysis fluid in the RO system when continuous running of OHDF was performed. In addition, we also assumed that the loss of drugs or useful substances from circulating blood by OL-CHDF required attention. To achieve safe and effective treatment of OL-CHDF in ICU, the appropriate protocols including maintenance of the RO system and staffing would be required.
