Journal of Japan Society for Blood Purification in Critical Care
Online ISSN : 2434-219X
Print ISSN : 2185-1085
Comparison of the IL-6 adsorption ability of two types of AN69ST hemofilter
Yukiko SennoTsuneyuki NakanouchiTetsuya OkazakiSyuusuke AoyagiRina IshiiTakayuki IkedaTadashi SuzukiTakuya KibayashiTomoko NiibeJunzi NishihataAtsushi IshikawaMakoto MiyashitaHiroki MatsuyamaTetsurou Takegami
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2017 Volume 8 Issue 2 Pages 132-136

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Abstract

【Aim】To compare the ability of sepXiris100® and sepXiris150® AN69ST hemofilters to adsorb serum IL-6. 【Methods】Patients with serum IL-6 concentrations≧1,000pg/mL at the start of therapy underwent continuous hemodiafiltration (CHDF) with sepXiris100® (1.0m2;n=10) or sepXiris150®(1.5m2;n=9) hemofilters. IL-6 clearance was measured 15min and 1, 24 and 48h after the start of therapy. 【Results】Mean IL-6 clearance at 15min, 1h, 24h, and 48h was 24.5±18.6, 8.8±7.8, 6.1±5.2 and 7.4±12.0mL/min, respectively, with sepXiris100®and 25.4±8.2, 11.8±5.3, -0.1±7.2 and 6.0±6.6mL/min, respectively, with sepXiris150®. 【Conclusion】There were no significant differences in cytokine adsorption by sepXiris100® and sepXiris150® hemofilters at any time point.

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© 2017, Japan Society for Blood Purification in Critical Care
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