Abstract
Pathphysiological and biochemical discussion about catatonia has developed, having been focused on the similarity with neuroleptic malignant syndrome, which was recognized with 20 years delay after the induction of antipsychotics. With respect to treatment, benzodiazepines and electroconvulsive therapy are the first line recommendation, while antipsychotics believe to be contraindication. To call these in question, consecutive fifty cases with catatonic features were analyzed.