Japanese Journal of Biological Psychiatry
Online ISSN : 2186-6465
Print ISSN : 2186-6619
Application of transcranial direct current stimulation in the treatment of schizophrenia for improvement of cognitive function
Kazuki Sueyoshi, Tomiki Sumiyoshi
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2022 Volume 33 Issue 2 Pages 82-86

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Abstract
Patients with schizophrenia present cognitive impairment in addition to positive and negative symptoms. Cognitive impairment of schizophrenia (CIS) is a distinct symptom, and is independent of motivation or general intelligence. Cognitive domains affected in schizophrenia include verbal learning memory, verbal fluency, attention, and executive function. Since CIS influences functional outcomes, pharmacotherapy and psychosocial approaches have been tested to enhancement cognition. However, the effect sizes of these treatments have been small, and side effects and/or the need of considerable human resources poses major challenges. For these reasons, non‐invasive brain stimulation methods, e. g., transcranial direct current stimulation (tDCS) , are attracting interest as a feasible and safe treatment. In this paper, we provide an overview of tDCS and its ability to alleviate CIS.
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© 2022 Japanese Society of Biological Psychiatry
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