Abstract
It is believed that the onset of schizophrenia involves complex interactions between genetic and environmental factors. Epigenetic approaches, such as DNA methylation analysis, provide a method for analyzing the influence of environmental factors at the molecular level. In the field of psychiatric disorders, comprehensive DNA methylation analysis, in addition to candidate gene analysis, has been widely conducted. The accumulation of large‐scale DNA methylation data has facilitated the application of various epigenetic clocks. Here, we summarize the current status of the application of epigenetic clocks in schizophrenia.