抄録
High performance liquid chromatography with native fluorescence detection is shown to be readily applicable to the selection determination of biogenic amine in urine. Measured via their native fluorescence emitted with an excitation wave length of 280nm, the emission filter 315nm. The maximum sensitivity of this method is in the pico-gram range.
This method is applied to alumina adsorption method. In this study we present our finding regarding the change of urine catecholamine.
The concentration values of urine catecholamine (NA, DA) in the depressive patients (16 cases) were lower than those in control group, and there was negative correlation between urinary noradrenaline excretion level and clinical symptom (Hamilton Rating Scale).
