抄録
The preparation and antigenic properties of 2-hydroxyestrone-bovine serum albumin (BSA) conjugate in which the hapten is linked to the carrier protein through the 15α position are described. The antiserum raised against this antigen in the rabbit showed a high affinity (Ka=1.3×109M-1) and excellent specificity to 2-hydroxyestrone, exhibiting little or no cross-reactivities for related steroids with an exception of 2-hydroxyestradiol (14.3%).
