Glycated Lipoproteins in Serum from Insulin-Dependent (IDDM) and Non-Insulin-Dependent (NIDDM) Diabetic Patients

Kunio Kobayashi; Naomi Ogasahara; Akira Matsuoka; Tohru Takumi; Hajime Nakamura

doi:10.14921/jscc1971b.20.3_153

Kunio Kobayashi, Naomi Ogasahara, Akira Matsuoka, Tohru Takumi, Hajime Nakamura

Author information

Keywords: glycated lipoprotein, insulin-dependent diabetes mellitus (IDDM), non-insulin-dependent diabetes mellitus (NIDDM), fructosamine, glycated pre β-lipoprotein, glycated albumin

JOURNAL FREE ACCESS

1991 Volume 20 Issue 3 Pages 153-155

DOI https://doi.org/10.14921/jscc1971b.20.3_153

Details

Abstract

We quantified and comparerd glycated lipoproteins (glc Lps) in serum from insulin-dependent (IDDM, ages 8-27 years, n=15) and non-insulin-dependent (NIDDM, ages 41-72 years, n=10) diabetic patients, and age-corresponding non-diabetic controls (Non-DM) by an agarose gel electrophoresis with nitroblue tetrazolium coloration. The fructosamine value of IDDM was higher than that of NIDDM, suggesting the accelerated glycation of serum proteins in IDDM.Glc pre β-Lp (glc VLDL) of NIDDM was significantly higher value(+246.2%) than that (+69.2%) of IDDM and glc albumin was slightly increased (IDDM) or not changed (NIDDM), compared with that of the age-corrsponding Non-DM controls.

Corresponding author

Register with J-STAGE for free!