Abstract
Measurements of the biochemicals in the serum of patients with liver diseases using the liver function tests involving guanase, multivariate analysis was performed in order to compare such measurements. By principal component analysis, these tests could be divided into the characteristic groups. The first principal component was considered to be relate to the severity of hepatocellular damage which belongs to guanase, aspartate aminotransferase, alanine aminotransferase, mitochondrial aspartate aminotransferase and lactate dehydrogenase. Multiple regression analysis revealed also that aspartate aminotransferase (p<0.001), alanine aminotransferase (p<0.01) and mitochondrial aspartate aminotransferase (p<0.05) were hepatic factors related to guanase. The equation of the multiple regression line was as follows: y(Gua)=2.43+8.68×10-3x(AST)+3.39×10-3x(ALT)+6.92×10-3x(m-AST).
