1996 Volume 25 Issue 4 Pages 229-234
Free radicals have been considered to play an important role in the pathogenesis of gastric mucosal lesions. We investigated the lipid radical-scavenging effect of antiulceratives such as Teprenone, Praunotol, Gefarnate, Sofalcone, Rebamipide and Benexate Hydrochloride Betadex using AMVN-induced peroxidation of linoleic acid. Teprenone did not affect the oxygen uptake rate (R) in the lipid peroxidation but prolonged the initiation time of the oxygen uptake (Tinh), Praunotol and Gefarnate reduced R but did not prolong T inh, Sofalcone, Rebamipide and Benexate Hydrochloride Betadex did not affect either R or T inh.
