臨床化学
Online ISSN : 2187-4077
Print ISSN : 0370-5633
ISSN-L : 0370-5633
血清Carboxypeptidase A活性の臨床的意義 (第2報)
血清Carboxypeptidase A活性と膵外分泌機能検査との関連について
田中 航志郎山片 重法西本 儀正山本 雅規藤井 暁関 淳一和田 正久奥田 清
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1976 年 4 巻 3-4 号 p. 291-297

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The relationships between the serum Carboxypeptidase A activity (CPase) and the results of exocrine function tests of the pancreas were studied. The following results were obtained.
(1) Concerning the relationships between the CPase and three factors in pancreozymin-secretin (PS) test, significant correlation was observed between CPase and total amylase output (r=0.571, p<0.005) or maximum bicarbonate concentration (r=0.415, p<0.05), but no significant correlation was observed between CPase and volume flow per kilogram.
(2) While 80% of patients with normal level of CPase was also within normal ranges in PS test, about 70% of patients with abnormal low level of CPase activity, we found any degree of dysfunction in PS test.
(3) No significant correlation was found between CPase and the results of 131l-triolein test.
(4) Low levels of CPase were observed in patients whose pancreatic scanning showed abnormality. It seems to be significantly correlated between the CPase activity in serum and the results of the exocrine function tests of pancreas.
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