Japanese Journal of Clinical Immunology
Online ISSN : 1349-7413
Print ISSN : 0911-4300
ISSN-L : 0911-4300
Feature Articles
Monocyte/Macrophage and TNFα-induced adipose related protein (TIARP) in rheumatoid arthritis
Isao MATSUMOTO
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2016 Volume 39 Issue 5 Pages 455-459

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Abstract

  In the pathogenesis of rheumatoid arthritis (RA), TNFα and IL-6 are proved to be crucial cytokines. Monocyte and macrophage are thought to produce these cytokines, as well as the source of cells becoming osteoclast in RA. In this review, I will discuss the role of monocyte/macrophage and the recent topic of negative regulator of arthritis such as TNFα-induced adipose related protein in RA.

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© 2016 The Japan Society for Clinical Immunology
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