A case of pustulotic arthro-osteitis with Basedow's disease

Abstract

A 55-year-old woman with pustulosis palmaris et plantaris (PPP) presented with sudden hearing loss (SHL). After steroid therapy for SHL, she had lumbago, pain of sterno-cost clavicular joints, sweating, and palpitation. The bone scan showed accumulation of 99 mTc in sterno-cost-clavicular joints. On the basis of physical and endocrinological examinations, she was diagnosed as pustulotic arthro-osteitis (PAO) with Basedow's disease. Antithyroid drug therapy for Basedow's disease could control both thyroid function and arthralgia. She showed hypersensitivity to antimony chloride. After patch test, thyroid function, arthralgia and PPP were worsen. Removal of antigen from oral cavity resulted in one year remission of PAO.