2020 Volume 3 Issue 2 Pages 362-369
A 64-year-old Japanese female visited our clinic after developing severe dermatitis and bullae on her fingers. She had started to make accessories using ultraviolet（UV）-cured acrylic resin a month ago, during which she wore cloth gloves or disposable polyethylene gloves. After she made the accessories the second time, she developed mild swelling, pain, and itching in her fingers, which subsided within a few days after the application of an over-the-counter ointment. After she made the accessories the third time, she developed severe hand dermatitis and visited our clinic. Patch tests using 1%, 0.5%, and 0.1% UV-cured acrylic resin and an accessory as is produced positive results on days 2, 3, 7 and 10. Further tests using several monomers of acrylic resin produced positive results for 0.1% 2-hydroxyethyl acrylate（2-HEA）on days 2, 3, 7 and 12, and doubtful reactions for 2% 2-hydroxyethyl methacrylate（2-HEMA）on days 3, 7 and 12. Tests of 1% HEMA produced negative results. As the UV-cured acrylic resin contained 2-HEA at a concentration of 0.94%, we diagnosed the patient with allergic contact dermatitis caused by 2-HEA and determined that she had become sensitized to acrylic resin within two weeks after making accessories. Resin allergies can develop when making accessories as well as during dental treatment or when wearing artificial nails or cosmetics. It is necessary to be aware that patients should not touch acrylic resin with their bare hands or when wearing disposable gloves; i.e., disposable gloves are insufficient for protecting against sensitization to acrylic resin.
（日本皮膚免疫アレルギー学会雑誌, 3（2）：362-369, 2020）
