臨床薬理
Online ISSN : 1882-8272
Print ISSN : 0388-1601
ISSN-L : 0388-1601
Effect of the Chinese Tienchi Ginseng on Blood Pressure in Stroke-prone Spontaneously Hypertensive Rats
Masaru MINAMIHiroko TOGASHIMachiko SANOIwao SAITOHideya SAITO
著者情報
キーワード: Tienchi ginseng, blood pressure, SHRSP
ジャーナル フリー

1984 年 15 巻 4 号 p. 479-487

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One week of oral administration of Chinese Tienchi ginseng (500 mg/kg/day) produced significant decrease in blood pressure during the period of rapid rise in blood pressure in stroke-prone spontaneously hypertensive rats (SHRSP). At 20 weeks old, a significant difference in blood pressure was noted both between the pre-(218.3±9.7 mmHg) and post-(202.9±9. 2 mmHg) Tienchi treated groups (P<0.02) and between the non-drug control (217.3±6.8 mmHg) and the Tienchi treated SHRSP (P<0.02). These findings indicate that Tienchi ginseng produced significant inhibition of the hypertension development process in SHRSP.

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© The Japanese Society of Clinical Pharmacology and Therapeutics
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