抄録
The effect of sodium nitroprusside on adrenaline-induced pulmonary edema was studied.
Pulmonary edema was induced in rabbits by intravenous infusion of adrenaline. The marked hemodynamic changes observed were: rise in systemic arterial pressure, reduction of left ventricular output, reduction of renal blood flow, elevation of left atrial pressure, and increase of pulmonary blood volume. When sodium nitroprusside was injected about 1 min after the start of the adrenaline infusion, the hemodynamic changes were suppressed or reversed, and pulmonary edema was prevented very effectively. However, maintenance of the renal blood flow was inadequate.
