2014 Volume 2 Issue 1 Pages 36-43
The improvement of immunosuppressive drugs dramatically reduced the acute allograft rejection episode which was the main reason for the allograft loss in the past. In recent years, the main reason for the renal allograft survival are chronic rejection, death with functioning allograft, and recurrent glomerulonephritis. Among these, recurrent glomerulonephritis, which is the third reason for renal allograft loss, were extensively investigated and recent works showed that the renal allograft survival in IgA nephropathy were worse than that had expected. The recurrent IgA nephropathy occurred in the long term observation and that could affect the worse allograft survival over 12〜15 years after renal transplantation. In this context, recurrent IgA nephropathy is now an important topic in recurrent glomerulonephritis. Up to now, several works clearly demonstrated the risks, diagnosis, prevention and treatment for recurrent IgA nephropathy. This review focused on patients with IgA nephropathy who underwent renal transplantation and discussed mainly recurrent IgA nephropathy.
