Workshop
Which are the Optimal Tonometers for Different Animal Speices?
—Cynomolgus Monkey—
1993 Volume 12 Issue 3-4 Pages 3-4_41-3-4_46
Details
1993 Volume 12 Issue 3-4 Pages 3-4_41-3-4_46
To determine an applicable tonometer for measuring the intraocular pressure (IOP) in cynomolgus monkeys, the properties of six kinds of tonometer were compared. The IOP was measured in a total of 53 cynomolgus monkeys varying in age from 10 weeks to 20 years old, which were bred and kept at Tsukuba Primate Center for Medical Science, NIH Japan, using 6 commercially available tonometers: SCHIϕTZ, ALCON, TONO-PEN, PERKINS, TOPCON, and KEELER.
The mean IOP of clinically normal cynomolgus monkeys was 16.4±3.1 (range: 9.8-24.4) mm-Hg, using SCHIϕTZ, 16.1±3.9 (7.3-24.8) mm-Hg, using TONO-PEN and 15.2±4.3 (6-28) mm-Hg, using KEELER. Statistically significant correlations were obtained between IOP determined by TONO-PEN and SCHIϕTZ (r=0.771, p=0.0001), by TONO-PEN and KEELER (r=0.590, p=0.0001), and by SCHIϕTZ and KEELER (r=0.355, p=0.0006). In conclusion, it was judged that SCHIϕTZ, TONO-PEN and KEELER were applicable to the measurement of IOP in cynomolgus monkeys on the basis of their utilizability as well as the accuracy of results obtained.
