1997 Volume 16 Issue 3-4 Pages 3-4_111-3-4_114
The progressive degeneration was found at the macular area of both eyes in a colony-born 128 months old female cynomolgus monkey by using indocyanine green video-angiography (ICG) and the fluorescence angiography (FAG). By the fundascopic examination, slight abnormal changes were found in the macular area at the age of 30 months and they progressively got worse. At the age of 128 months, the legion was expanded into an ellipsoidal shape centering at the fovea centrialis with the horizontal span of approximately four times of the diameter of the optic disc and the longitudinal span of approximately two times of the diameter of the optic disc. Hyperfluorescent parts of micro-granular shape corresponding to the degenerated lesion were demonstrated by FAG. The findings obtained by the later stage of ICG suggested the choroidal neovascularization occurred in the lesion.
