2002 Volume 21 Issue 1-2 Pages 39-42
Ophthalmologic examination of a 14-month-old male beagle revealed that the right optic disc was atrophic and abnormal in color and the retina was supplied by a reduced number of arteries. The light-stimulated pupillary reflex was weak and became considerably weaker with age. Histopathological examination revealed a decreased number of nerve fibers, an increased amount of collagen fibers and gliosis in the right optic nerve, and also vacuolation in the nerve fiber layer, a decreased number of ganglion cells and thinning of the inner plexiform layer of the retina in the right eye. Based on the above findings, we confirmed that the lesion was situated along the right descending optic nerve somewhere between the retina and the optic chiasm. We concluded the lesion was the result from a circulatory disturbance.