2010 Volume 29 Pages 25-28
A white and round raised focus (about 2 mm in diameter) with a few hairs was macroscopically observed in the cornea of the right eye from a male among Crl:CD(SD) rats which were purchased for a toxicity study at 5 weeks of age. During one year after the discovery, there were no changes in other corneal regions, anterior portion, optic media or fundus oculi except that the raised focus increased in roundness to form a hemispheric shape and lost it's hairs. Histopathological examination conducted at 59 weeks of age revealed normal skin structure consisting of epidermis, dermis with cutaneous appendages (hair follicles, hair roots and sebaceous glands) and subcutaneous adipose tissue. From these findings, the lesion was diagnosed as a corneal dermoid.
