Scleral Staphyloma Accompanied with Congenital Lesions such as Microphthalmia in a Crl:CD(SD) Rat

Abstract

Microphthalmia and a raised focus with cystic appearance at the junction of cornea and conjunctiva were observed in the right eye of a male Crl:CD(SD) rat. Ophthalmological examination revealed corneal opacity and vascularization around the raised focus, and persistent hyperplastic primary vitreous (PHPV) in the vitreous body nearby the raised focus. Histopathological examination revealed that the raised focus showed cystic structure composed of scleral components, and diagnosed as scleral staphyloma. It was considered that scleral staphyloma in this case was incidentally formed accompanying with congenital lesions such as microphthalmia.