CAPD with Icodextrin solution preserved the residual renal graft function and improved the quality of life in cadaveric renal transplanted ESRD patients with deteriorated graft function

Abstract

In this paper, we report a patient in whom residual renal graft function was successfully preserved using continuous ambulatory peritoneal dialysis (CAPD) with Icodextrin solution at reintroduction of dialysis after deterioration of graft function. A 70-year-old female underwent cadaver renal transplantation in 2001 after two years of hemodialysis due to end stage renal disease. Renal graft function deteriorated gradually over several years, and CAPD was reintroduced in June 2004. However, we encountered difficulty in controling her water balance and she developed edema and cardiac enlargement. In September 2004, we changed the CAPD prescription from 1.5% dextrose to Icodextrin solution at night. CAPD with Icodextrin solution increased her urine volume and corrected her body fluid status, CTR (cardiothracic ratio) and improved lipid metabolism and nutritional status. In this case, CAPD with Icodextrin solution contributed markedly to preserving residual renal graft function and finally improved her quality of life as evaluated by SF-36 (short form 36).