Causes of chronic kidney disease, assessed by diabetic retinopathy and albuminuria： Effects on life prognosis of diabetics starting chronic dialysis

Abstract

[Aim] To clarify whether causes of chronic kidney disease affect the life prognosis of people with diabetes starting chronic dialysis. [Methods] This was a retrospective cohort study of 857 participants with diabetes beginning chronic dialysis. Diabetic nephropathy was defined as having diabetic retinopathy and a urinary albumin‒to‒creatinine ratio≥300 mg/g (or urinary protein≥0.5 g/day). The outcome was all‒cause mortality. Hazard ratios were estimated based on a multivariable Cox proportional hazards model. [Results] During the median follow‒up period of 4.7 years, 208 died. The adjusted hazard ratio (95％ confidence interval) of people with diabetic nephropathy (vs. those with non‒diabetic nephropathy) for the outcome was 0.827 (0.496, 1.380, p＝0.468). [Conclusion] The results suggested that there are no effects of causes of chronic kidney disease on the life prognosis of people with diabetes starting chronic dialysis.