Abstract
Heparin free hemodialysis by EVAL (ethylene Vinyl alchol copolymer) H. F dialyzer, we have successfully performed with total of 466 dialysis for patients with hight bleeding risk and regular H. D. patients.
Prior to dialysis, dialyzers were washed out with 1 L heparinized saline (6000u) or 1 L saline containing gabexate mesilate (400mg), and then dialysis was performed without anticoagulant for patients during H. D. Our laboratory studies have shown that these H. D. do not cause any problem in comparison with ordinary H. D..
This is considered to be due to blood compatibility of EVAL itself and antithrombogenenicity arising from surface heterogeneity of unique microporous inner structure of EVAL.