Abstract
Clinical comparison was made of treatments with bicarbonate dialysis (BC-HD) and with acetate dialysis (AC-HD), in long-term (over 8 years) hemodialysis patients.
Patients treated with BC-HD were 8 males and 3 females, with a mean age of 46.1 years and a mean hemodialysis term of 10.3 years. All were patients with acetate intolerance. Patients treated with AC-HD were 6 males and 6 females with a mean age of 46.8 years and a mean hemodialysis term of 10.5 years.
We determined the means of biochemical and hematological measurements, gas analysis, and frequency of adverse symptoms such as headache, nausea and vomiting, during three months in each of the years 1978, 1981, 1982, 1985 and 1987.
Blood acetate was measured in 1978 and 1987, and C-PTH and the ejection fraction were measured in 1987.
Results: there was no significant difference between BC-HD and AC-HD in the biochemical and hemotological data, gas analysis, C-PTH, acetate, frequency of adverse symptoms, and ejection fraction. We concluded that BC-HD is useful for patients with acetate intolerance, and AC-HD would suffice for other patients.
