A case of the most severe heart failure with congenitally corrected transposition of great arteries and dextrocardia who was successfully treated by cardiac resynchronization therapy

Abstract

Heart failure (HF) due to a failing right ventricle (RV) functioning as a systemic chamber in patients with congenitally corrected transposition of great arteries (C-TGA) is often encountered and is now a therapeutic challenge for adult cardiologists. Whether cardiac resynchronization therapy (CRT) may achieve a satisfactory outcome for these patients, especially for those with end-stage HF, has been not established in contrast to its established efficacy in patients with left ventricular dysfunction and electromechanical dyssynchrony. Here, we report a 41-year-old patient with inotrope-dependent RV failure accompanied by C-TGA and dextrocardia drastically improved by CRT, as well as a review of the literature.