硫酸ストレプトマイシン使用者の前庭温度眼振反応

統計的観察

抄録

Vestibular and auditory funtion tests were performed in patients who had received streptomycin sulfate (SM) injections. The caloric test and pure tone audiometory were chosen as tests of vestibular and auditory functions, respectively. The results of the caloric tests were correlated with auditometry results, age, dose of SM and renal function.
The reduction of the maximum slow phase velocity was 0.70±0.15°/sec/g (mean±SE). There seemed to be a relationship between the reduction of the maximum slow phase velocity of caloric nystagmus and the total dose of SM, but the hearing threshhold did not change when the total SM dose was increased. The reduction of the maximum slow phase velocity of caloric response in the older patients seemed to be larger than in the younger patients. The weekly dose of SM and the renal function were not related to the vestibular function. These results suggest that the caloric test is useful in detecting not only vestibular dysfunction but also hearing impairment. It is important to check the response to the caloric test to prevent hearing loss due to SM injections.