Abstract
1. We evaluated the effects of ATP (adenosine triphosphate), dilazep dihydrochloride and vinpocetine by testing vertebral arterial blood flow with the ultrasonic doppler method. Each drug was administrered orally to patients with vertigo or dizziness for 4 to 8 weeks.
2. The rate of clinical efficacy of ATP was 88.9%, that of dilazep dihydrochloride was 87.5%, and that of vinpocetine was 73.7%. No adverse reaction was observed.
3. In the patients who received vinpocentine, there was a significant increase of vertebral arterial blood flow and a significant decrease of the right left difference in that flow.
4. In 10 patients whose vertebral arterial blood flow before administration was normal, the clinical efficacy rate was high, 100% and 78.3% in the decreased blood flow group, and 78.3% in the right-left difference blood flow group.
5. In the patients with abnormal vertebral arterial blood flow before treatment and after with normal flow, after treatment, the rate of efficacy was higher than in the patients with abnormal flow after treatment.
6. Administering ATP and dilazep dihydrochloride together had a good clinical effect and improved vertebral arterial blood flow.
