Abstract
Typing of Class I antigen of HLA-A, Aw, B, Bw, Cw and Class II antigen of HLA-DR, DRw, DQw was done in 44 Japanese patients with Meniere's disease (21 bilateral and 23 unilateral). None of them had a family history of Meniere's disease.
HLA-Bw 52 antigen was found in 23% and HLA-DRw8 in 8% of the patients. The frequency of the former was higher and that of the latter was lower than in healthy control (N=120); however, the difference was not significant after corrections were done for the number of antigens tested.
There was no significant difference in the frequency of the antigen in those with bilateral or unilateral involvement.
