Vogt-小柳-原田病における臨床的検討
1992 年 51 巻 Suppl-8 号 p. 138-142
詳細
1992 年 51 巻 Suppl-8 号 p. 138-142
Vogt-Koyanagi-Harada (Harada's) diseases is a systemic and autoimmune disorder consisting of uveitis, hearing loss, vertigo, vitiligo and premature graying of the hair involving melanocytes. Twenty-four patients with Harada's disease were studied clinically.
Mild hearing loss was noted in 28 ears (58.3%). The short increment sensitivity index (SISI) test was positive for the recruitment phenomenon in 6 of the 10 ears tested. Three patients complained of vertigo (12.5%), but they should no rotatory vertigo or horizontal nystagmus.
Prednisolone therapy was tried for one month, hearing was improved in 15 ears (53.6%).
These clinical findings suggest disorder of the inner ear. Therefore, we thought that it was important to discuss Harada's disease as an autoimmune disease to elucidate the pathogenesis of the inner ear problem.
