Guinea pigs with experimental endolymphatic hydrops were treated with glycerol, bifemelane hydrochloride or diphenidol hydrochloride and observed for morphological changes in the affected inner ear.
1. Treatment with any of the three drugs im-proved inner ear circulation.
2. The degree of reduction of endolymphatic hydrops tended to be associated with that of strial atrophy.
These results suggest that reduction of endo-lymphatic hydrops depends on strial function.
