内リンパ嚢局所免疫反応による前庭機能異常
外リンパ抗体価と自発眼振との関係
1993 年 52 巻 Suppl-9 号 p. 144-147
詳細
1993 年 52 巻 Suppl-9 号 p. 144-147
The relationship between an episode of spontaneous nystagmus and perilymph antibody levels following secondary immune reaction in the endolymphatic sac (ES) was examined in guinea pigs. Spontaneous nyztagmus was observed in 28 out of 46 animals. From day 2 to 7, the mean perilymph antiboody levels in the animals demonstrating spontaneous nystagmus were significantly higher than in animals without nystagmus. However, from day 14 to 28, no significant difference was seen in the mean perilymph antibody levels between the animals with and without spontaneous nystagmus. These results suggest that immune reaction in the ES may actually induce vestibular disorders.
