Equilibrium Research
Online ISSN : 1882-577X
Print ISSN : 0385-5716
ISSN-L : 0385-5716
Ibudilast (Ketas®) in Meniere's Disease
Yatsuji ItoKeisuke MizutaMitsuhiro AokiTakahiko KumadaShigeo SawaiShinji SakumaTomoo SuzukiHideo MiyataHikari Koizumi
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JOURNAL FREE ACCESS

1994 Volume 53 Issue 3 Pages 429-436

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Abstract
To assess the efficacy of Ibudilast in Meniere's desease, we randomly selected 15 patients with this desease seven males and eight females aged 30 - 73 years.
We administered three capsules of Ketas® every day to these patients and investigated the following : 1) effect of treatment on vertigo, 2) effect of treatment on damage to the inner ear, 3) effect of treatment on recurrent attacks of vertigo. The effect of treatment on recurrent attacks of vertigo was evaluated by comparing the number of attacks a months after the start of treatment with the number before treatment.
Treatment reduced recurrent attacks of vertigo in 11 patients (73%).
No side effects were reported in this study.
We conclude that Ketas® may be an effective drug for Meniere's disease.
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© Japan Society for Equilibrium Research
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