Abstract
The therapeutic effect of ibudilast, a cerebral vasodilator, was evaluated in 106 patients with vertigo or dizziness. The patients were given a 10 mg capsule of ibudilast 3 times a day for over 4 weeks. In 77 patients (72.6%), symptoms and/or signs were reduced. Mild side-effects were noted in 3 patients (2.8%). These results suggest that ibudilast is a clinically useful drug for the treatment of vertigo or dizziness. A questionnaire consisting of 14 questions was used to evaluate the handicaps in everyday life due to dizziness in 25 patients. A discrepancy was noted between the doctor's evaluation of improvement and the patient's selfassesment. It appeared that patients with emotional disturbances and limited social activity due to dizziness perceived greater handicaps.
