Journal of Structural and Functional Genomics
Online ISSN : 1345-711X
ISSN-L : 1345-711X
Mapping of 19032 mouse cDNAs on mouse chromosomes
Itaru YamanakaHidenori KiyosawaShinji KondoTetsuya SaitoAkira ShinagawaKatsunori AizawaShiro FukudaAyako HaraMasayoshi ItohJun KawaiKazuhiro ShibataTakahiro ArakawaYoshiyuki IshiiYoshihide Hayashizaki
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2001 Volume 2-pre Issue 1 Pages L72-L86


Finding genes by the positional candidate approach requires abundant cDNAs mapped to chromosomes. To provide such important information, we computationally mapped 19032 of our mouse cDNAs to mouse chromosomes by using data from public databases. We used 2 approaches. In the first, we integrated the mapping data of cDNAs on the human genome, known gene-related data, and comparative mapping data. From this, we calculated map positions on the mouse chromosomes. For this first approach, we developed a simple and powerful criterion to choose the correct map position from candidate positions in sequence homology searches. In the second approach, we related cDNAs to expressed sequence tags (EST) previously mapped in radiation hybrid experiments. We discuss improving the mapping by combining the 2 methods.

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© 2001 Kluwer Academic Publishers
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