2022 Volume 37 Issue 1 Pages 53-59
Objectives：In this study, we investigated the effects of Neonisin-e oral care gel （Oral Peace, Food Care Co., Ltd.） on oral candidiasis and tongue coating.
Methods：The study included 40 patients （mean age 76.0±14.0 years） with mild oral candidiasis and tongue coating. The participants were categorized into two groups based on the period of time. The intervention group used the Neonisin-e oral care gel, and the control group used an oral care gel without Neonisin-e, before and after oral care. The intervention was performed over 3 weeks；the Candida albicans count on the tongue surface and the Tongue Coating Index （TCI） were measured before and after intervention. The Wilcoxon signed rank test was used to compare the C. albicans counts and TCI scores. The statistical significance level was set at 0.05.
Results：In the intervention group, the C. albicans count decreased significantly from 5 （4-6） to 3 （2-4） after the 3-week intervention （p＜0.001）. The C. albicans count showed a similar decrease after the 3-week intervention in the control group, from 5 （4-6） to 3 （1-5） （p＝0.030）. The TCI decreased significantly after 3 weeks in both groups （intervention group p＝0.001, control group p＝0.003）.
Conclusions：The use of oral care gel for 3 weeks was effective for treatment of oral candidiasis and tongue coating.
