Purpose：“Pa-ta-ka-ra”exercises for functional training of the tongue and lips are carried out to prevent oral frailty in nursing homes. However, the effects of the training on cognitive function and oral function are not clear. Therefore, we investigated the effects related to cognitive function, lingual muscle and orbicularis oris muscle.

　Methods：Sixty older adults （66–98 years old） were divided into two groups：the training group （T group） and the no-training group （N group）. The subjects of the T group performed two trainings before meals every day, moving the tongue in and out, and performing the “Pa-ta-ka-ra”exercise, which is training involving repeating each sound of “pa”, “ta” and “ka”. All subjects were subjected to measurement of cognitive function （MMSE）, wettability of the tongue, tongue and lip function （ODK）, and tongue pressure and lip pressure every 3 months until 21 months. We compared the value of each time in each group and the difference between the first value and each time in both groups.

　Results：In the T group, there was a significant difference between the wettability of the oral cavity before training and the value at 21 months after training. The tongue pressure and the lip pressure after 12 months were significantly higher than the values before training. Comparing both groups, there were significant differences in MMSE after 18 months and ODK at 9 months and 21 months. The degree of change of the tongue pressure after 9 months and the lip pressure at 21 months in the T group were significantly higher than the values in the N group.

　Conclusion：The continuation of the functional training for the tongue and lips raised the tongue pressure and lip pressure, suggesting that the training was effective for maintaining cognitive function and pronunciation function.

　Keeping dentures clean is essential for maintaining the health of denture wearers. There are several reports on evaluating the plaque removal effect of cleaning using a plaque model in vitro. However, a plaque model that reflects the bacterial species of practical denture plaque has not been developed yet. In this study, we analyzed the flora of complete denture plaque by comprehensively sequencing the 16S rRNA gene using a next-generation sequencer. A new plaque model was built using the major constituent bacterial species and the effectiveness of the removal effect of denture cleanser was assessed. All plaques were collected from the denture base part and analyzed using the next-generation sequencer. It was clarified that Streptococcus salivarius, Veillonella dispar, Actinomyces meyeri, and Rothia mucilaginosa were dominant in complete denture plaque. A new plaque model was reconstructed on resin using the abovementioned four bacteria and a fungus, Candida albicans. When the viable cell count was measured after washing the plaque model, the cleaning agent achieved about a 4 log reduction against microorganisms in the plaque model. Additionally, confocal laser scanning microscopy observation of the plaque model with the LIVE/DEAD BacLight Bacterial Viability Kit suggested that the cleanser peeled plaque from resin and killed almost all bacterial strains in the plaque remaining on the resin. In this study, we created a new denture plaque model and constructed a basis for evaluating complete denture cleanser.

　Objective：Several welfare policies including long‒term preventive care are being carried out to extend the healthy life expectancy and improve QOL of the older adults in Japan. On the other hand, due to the progress of medicine, radical surgery and salvage treatment are performed on older cancer patients, reducing their QOL after treatment. However, there are no studies on the effects of long‒term preventive care for older patients after cancer treatment. The purpose of this study was to compare older oral cancer patients with older ordinary people, focusing on long‒term preventive care.

　Materials and Methods：Sixty‒four older post‒treatment oral cancer patients who visited the Department of Oral Rehabilitation, Showa University Dental Hospital were recruited in this study. The older ordinary people were 4,047 older people in Ota Ward investigated in 2020. A questionnaire survey was done.

　Results and Discussion：Older post‒treatment oral cancer patients had a significantly lower Instrumental Activities of Daily Living score than the ordinary older adults in Ota Ward. However, the rate of going out at least once a week was higher and the subjective view of health was significantly higher in the patients. Although the rate of participation in small learning or cultural groups and community activities tends to be higher, the rate of participation in social activities decreased in the patients. In addition, a significant decrease in swallowing function was observed in the patients compared to their function half a year earlier. The decrease of swallowing function may have been due to “accelerated”aging and oral frailty.

　Conclusion：It is considered that a support system and program for maintaining oral function and decreasing social distress are needed for older patients after treatment for oral cancer.

　Objectives：In this study, we investigated the effects of Neonisin-e oral care gel （Oral Peace, Food Care Co., Ltd.） on oral candidiasis and tongue coating.

　Methods：The study included 40 patients （mean age 76.0±14.0 years） with mild oral candidiasis and tongue coating. The participants were categorized into two groups based on the period of time. The intervention group used the Neonisin-e oral care gel, and the control group used an oral care gel without Neonisin-e, before and after oral care. The intervention was performed over 3 weeks；the Candida albicans count on the tongue surface and the Tongue Coating Index （TCI） were measured before and after intervention. The Wilcoxon signed rank test was used to compare the C. albicans counts and TCI scores. The statistical significance level was set at 0.05.

　Results：In the intervention group, the C. albicans count decreased significantly from 5 （4-6） to 3 （2-4） after the 3-week intervention （p＜0.001）. The C. albicans count showed a similar decrease after the 3-week intervention in the control group, from 5 （4-6） to 3 （1-5） （p＝0.030）. The TCI decreased significantly after 3 weeks in both groups （intervention group p＝0.001, control group p＝0.003）.

　Conclusions：The use of oral care gel for 3 weeks was effective for treatment of oral candidiasis and tongue coating.