Abstract
A 73-year-old woman presented to our hospital in June 2013. She underwent computed tomography (CT) showing enlarged lymph nodes on the lesser curvature of the stomach. Upper gastrointestinal tract endoscopy showed a slightly depressed lesion, approximately 40 mm in diameter, in the greater curvature of the lower gastric body. Based on biopsy results, she was diagnosed with diffuse large B-cell lymphoma (DLBCL). A thorough examination revealed limited-stage DLBCL in clinical stage II-1. With a total of six cycles of THP-COP (therarubicin, cyclophosphamide, vincristine, prednisolone) therapy with an anti-CD20 monoclonal antibody (rituximab) (R-THP-COP therapy), she achieved complete remission. At a community health check-up in May of 2013, gastric X-ray had been performed, but the lesion had not been detected. This failure was attributed to difficulty demonstrating such a lesion by double contrast study in the supine position, since the lesion overlapped with barium flowing into the duodenum, and to reliance on population-based examinations lacking the compression technique.
