IA1期の子宮頸癌患者に対する腹腔鏡下子宮全摘術の有用性：後方視的コホート研究

抄録

Objective: The objective of this study was to verify the feasibility of laparoscopic hysterectomy in patients with stage IA1 cervical cancer.

Methods: The current study was based on the available data for 103 patients with stage IA1 cervical cancer who were admitted at the Hokkaido Cancer Center between January 2000 and December 2016. The distinct parameters for each patient, including the operation time, estimated blood loss, blood transfusion, recurrence, and survival were compared between the conization group (n=36) and the hysterectomy group (n=67). Within the hysterectomy group, the treatment outcomes were compared between the non-laparoscopic hysterectomy group (n=31) and the laparoscopic hysterectomy group (n=36).

Results: In the present study, there was only one patient with cancer recurrence who underwent cervical conization. The rate of cancer recurrence in the conization group was substantially higher than in the hysterectomy group (2.8% vs. 0%, P=0.18). The estimated blood loss in the laparoscopic hysterectomy group was significantly less in comparison with the non-laparoscopic group (213g vs. 46.5g, P=0.0017). The rate of patients who received blood transfusion in the laparoscopic hysterectomy group was higher than that in the non-laparoscopic group (9.7% vs. 0%, P=0.056).

Conclusion: Thus, it can be concurred that laparoscopic hysterectomy is a safe surgical procedure in patients with stage IA1 cervical cancer when performed by experienced surgeons at the tertiary centers.