癒着防止吸収性バリア アドスプレー^®による癒着防止効果の検討

抄録

Objective: To evaluate the anti-adhesive effect of AdSpray^®.

Methods: This study included five patients who underwent second-look laparoscopy (SLL) after their initial laparoscopic surgery with AdSpray^® at our hospital between December 2017 and December 2018. The adhesion status was evaluated based on the findings of the initial surgery and SLL to determine the anti-adhesive effect. Adhesion was evaluated using the adhesion score of the revised American Society for Reproductive Medicine classification, which is used to classify the severity of endometriosis.

Results: Of the five patients, a case of myomectomy showed no adhesion at the SLL. Another patient who underwent ovarian tumor enucleation and myomectomy had high adhesion scores at both the initial surgery and SLL. The other three cases were for endometriosis with chocolate cysts. Although their adhesion scores decreased at SLL, adhesion re-formation or newly developed lesions were observed around the adnexa.

Conclusions: The results of this study revealed that the use of only anti-adhesive materials, such as AdSpray^®, might be insufficient to prevent adhesions, depending on the adhesion status at the initial surgery, procedural maneuvers, and disease.