卵巣予備能保護を目的とした腹腔鏡下卵巣嚢胞摘出術の止血に酸化再生セルロースパウダーを用いる有用性

抄録

Objective: The treatment strategy for ovarian tumors is often uncertain when a patient wishes to have children. Especially in the case of endometriotic cysts, although pre-assisted reproductive technology ovarian cystectomy does not improve the live birth rate, surgery may be selected considering the symptom and the infertility treatment course. In such cases, it is necessary to pay attention to selecting the hemostatic method for ovarian reserve. It has been reported that hemostasis with suture / hemostatic sealant has a smaller decrease in serum anti-Müllerian hormone (AMH) level than with bipolar coagulation. We focused on this method using a hemostatic sealant.

Methods: We used Oxidized Regenerated Cellulose Powder as a hemostatic method when performing laparoscopic ovarian cystectomy. Nine patients wishing to have babies were included. The serum AMH concentration was investigated before and 3 months after surgery.

Results: The average change in AMH before and after surgery was 97.3%, showing almost no decrease.

Conclusions: Using Oxidized Regenerated Cellulose Powder for hemostasis in laparoscopic ovarian cystectomy was shown to prevent a decrease in AMH level after surgery; this method could provide a sufficient protective effect on ovarian reserve.