猿島肝炎(伝染性肝炎)の研究

流行初期の疫学現象の分析

抄録

Provincial prevalence of infectious hepatitis is increasing in Japan. Though the germ has been accepted to be a virus (or viruses), it has been able to test by neither virological technique nor immuno-serological method ; the diagnosis of the disease is subjected to the clinical, histopathological or biochemical researchs. As long as it is the infectious disease, however, there may be latent infection or incomplete symptoms, and there may be various types of the disease. Therefore, it may be questionable somehow to forecast the prevalence of such a disease depending on the judgement on the epidemiological phenomena in the early period of the disease. The author was happened fortunately to contribute to treatment of Sashima hepatitis and researched how the epidemiological aspects in the early period was varied depending on the continuous pursue of the disease, and what tests should be employed in the early period of the prevalence. As there are many diseases that cause disturvance of liver such as infectious hepatitis in farm villages in Japan, other factors such as mercury poisoning and filariasis should be considered. The author at first recognized frequent outbreak of liver diseases, and confirmed the infectious hepatitis. Then, the disease was researched as grouping on sex, age and district; there was found out that the levels of positive urine urobilinogen had a relation with the provincial outbreak, and many patients had not been found out even a precise research in the early period. The serum transaminase evaluation was found out to be effective in early research. Though in the group which was thought to be normal, sometimes, presented some patients following the progress of the epidemic, it may be recommended to consider those who showed S-GPT higher than 50(Karmen unit) would be abnormal.