インフルエンザ流行の血清疫学的研究

―特に,地域差について―

抄録

This study was conducted to observe the regional difference of the prevalence of influenza. The sampled regions of this study were Sashima area, Ibaragi Prefecture and Shonai area, Yamagata Prefecture. In this study, HI antibody value in the serums sampled as the same time from the populations in both areas was determined. Strains of influenza virus in this experiment were A/Aichi/2/68 strain, A/Tokyo/6/73 strain, A/Yamanashi/20/75 strain, B/Tokyo/7/66 strain, B/Yamagata/1 773 strain, B/Gifu/2/73 strain, and B/Kanagawa/3/76 strain, which were prevailed in Japan in the past. In addition, to study the possibility of the re-prevalence of influenza due to the strains prevailed in the past, coutermeasure against Swine type influenza virus (HswlNl type strain) which now draws interest of the persons concerned was discussed. Consequently, it was confirmed that there were regional differences with different types of epidemic strains. In other words, A-type strain was presumed to have caused a severe prevalence in Sashima area then in Shonai area. In Shonai area, invasion and prevalence of the virus were confirmed, but the prevalence of that influenza was presumed to have been of moderate degree. Nearly the same tendency as with A-type strain was seen with B-type strain, while Shonai area was found as a result of the.serological analysis to have experienced a larger prevalence with B/Tokyo/7/66 strain. On the other hand, the possessed antibody to A/New Jersey/8/76 strain mostly indicated the past prevalences, while some relation with the pig was suggested in other cases, but the study failed to make confirmation for all cases.