肥満と血清Dopamine-β-hydroxylase活性

抄録

The relationship between obesity index and serum dopamine-β-hydroxylase (DBH) activity, which was considered to be a useful index as a sympathetic nerve activity, was examined on 55 males and 61 females over 19 years old who lived in Shiramine-village, Ishikawa Prefecture. The results obtained were as follows. 1) Frequency of obese persons, whose obesity indexes were over +10%, in females 2) Significant negative correlation between obesity index and serum DBH activity was observed in females. However, there was no significant correlations between them in males.was significantly high, compared with that in males. 3) The serum DBH activities in the obese females under 39 years old were significantly low, compared with that in non-obese females . The serum DBH activities in nonobese females tended to decrease with age. However, in obese females, the changes of the serum DBH activities with age were not observed. These results suggests that the sympathetic nerve activity in obese females might be depressed from youth.