Newborn Screening and Treatment in the History of the Development of Special Formula

Abstract

This study aims to clarify the influence of Japan introducing newborn screening in 1977 on the development of special formula for treating inborn errors of metabolism. A review of the Secretariat of Special Formula bulletins, medical journals, and the history of dairy enterprises shows how the introduction of newborn screening affected the development and medicalization of special formula. However, follow-up examinations revealed that some cases cannot be treated by dietary management or special formula, while others require no treatment at all. During this study, it therefore became evident that the development and medicalization of special formula alone cannot prevent the occurrence of disorders.