Chemoprevention for hereditary colorectal cancer

Abstract

Cancer chemoprevention is a cancer prevention method using chemical compounds, such as drugs, and is mainly targeted a high-risk group of cancer. Hereditary colorectal cancer includes familial adenomatous polyposis and Lynch syndrome. However, there is no standard drug therapy option aiming colorectal cancer prevention for them, i.e. it remains at the research level. Our research group is trying to develop the first cancer prevention drug in Japan. This article mainly overviewed clinical trials of colorectal cancer prevention using aspirin.