Abstract
A 68-year-old man, diagnosed as having triple lung cancer, underwent a right lower lobectomy 4 months after undergoing a left upper lobectomy. He developed acute lung injury, possibly because of massive bleeding, shock and blood transfusion during the surgery. Despite an improvement in lung oxygenation, he was unable to be weaned from mechanical support. We then changed our treatment goal to the start of home mechanical ventilation (HMV). As a result, his condition was improved remarkably, accompanied by adequate nutrition. On the 305th postoperative day, he returned home. HMV may be an option for improving the quality of life of patients who become ventilator-dependent.