2021 Volume 28 Issue 3 Pages 205-209
Posterior reversible encephalopathy syndrome (PRES) has been shown to have a favorable prognosis, but cases with neurological sequelae and death have also been reported. It is a disease that is not well recognized among pediatricians because there are few reports of pediatric cases, which may delay the diagnosis and timing of treatment intervention. A retrospective study was conducted to clarify the clinical features of PRES in pediatric patients. Thirteen cases were identified, with ages raging from 1 to 17 years old (median age 8 years old). All cases showed consciousness disorder, with seizure in 9 cases and hypertension in 11 cases. Immunosuppressants and anticancer agents were used in 11 cases. All had underlying diseases, mostly consisting of renal and hematological diseases. All cases demonstrated progression without any neurological sequelae. The clinical features of the cases in the present study were the same as those observed in previous studies. In children, an appropriate blood pressure evaluation may lead to an early diagnosis, timely intervention, and a consequent improvement in the prognosis of PRES in patients with consciousness disorder with seizure.
